doi: 10.1007/978-1-59745-401-8_12.
Measurement of glycosaminoglycan release from cartilage explants
- PMID: 17951660
- DOI: 10.1007/978-1-59745-401-8_12
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Measurement of glycosaminoglycan release from cartilage explants
Methods Mol Med.
2007.
Abstract
Quantitation of glycosaminoglycans (GAGs) in the form of aggrecan fragments released from cartilage in culture is a simple way to determine the efficacy of different cytokines alone or in combination in simulating cartilage catabolism. Two approaches for GAG assay are described, with special attention being paid to the advantages and limitations of each method.
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