High grade atrioventricular heart block in 2 adults with systemic lupus erythematosus

J Rheumatol. 1991 Dec;18(12):1926-8.


We describe 2 patients with systemic lupus erythematosus (SLE) and high grade atrioventricular (AV) block. In one patient anti-Ro antibodies were positive. This antibody has been associated with congenital complete heart block in children of mothers with SLE; however, its role in adult high grade AV block is not clear. We reviewed the 8 published cases of adults with SLE and high grade AV block. The possible mechanisms that could be implicated in the pathology of high grade AV block are discussed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Antibodies, Antinuclear / analysis
  • Electrocardiography
  • Female
  • Heart Block / complications*
  • Heart Block / diagnosis
  • Heart Block / immunology
  • Humans
  • Lupus Erythematosus, Systemic / complications*


  • Antibodies, Antinuclear
  • SS-A antibodies