Undifferentiated sebaceous carcinoma: an unusual childhood cancer

Pediatr Dermatol. 2007 Sep-Oct;24(5):501-4. doi: 10.1111/j.1525-1470.2007.00503.x.


Sebaceous carcinoma is an aggressive, adnexal, rare malignant tumor that may arise in ocular or extra-ocular sites. Extraorbital sebaceous carcinoma is exceptional in childhood. We report a 12-year-old boy with an ocular sebaceous carcinoma who was first seen with an asymptomatic firm, cutaneous nodule on the right eyebrow. The tumor developed slowly within 1 year. Histologically, it was an undifferentiated sebaceous carcinoma. The patient had surgery with wide surgical margins. He was alive and free from disease at a follow-up of 34 months. Close follow-up of this tumor is recommended because of the risk of aggressive behavior.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma, Sebaceous / pathology*
  • Adenocarcinoma, Sebaceous / surgery
  • Cell Differentiation
  • Child
  • Eyebrows / pathology*
  • Humans
  • Male
  • Neoplasms, Adnexal and Skin Appendage / pathology*
  • Neoplasms, Adnexal and Skin Appendage / surgery
  • Sebaceous Gland Neoplasms / pathology*
  • Sebaceous Gland Neoplasms / surgery