Dense-granule protein NcGRA7, a new marker for the serodiagnosis of Neospora caninum infection in aborting cows

Clin Vaccine Immunol. 2007 Dec;14(12):1640-3. doi: 10.1128/CVI.00251-07. Epub 2007 Oct 24.

Abstract

To investigate whether the production of an antigen-specific antibody is associated with Neospora caninum-induced bovine abortion, 62 serum samples were tested with an enzyme-linked immunosorbent assay using the recombinant antigens NcSAG1, NcSRS2, and NcGRA7. Our study suggested that NcGRA7 would be a new marker for the serodiagnosis of N. caninum infection resulting in abortion.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abortion, Veterinary / parasitology*
  • Animals
  • Antibodies / blood*
  • Antibodies / immunology
  • Antigens, Protozoan* / genetics
  • Antigens, Protozoan* / immunology
  • Antigens, Protozoan* / metabolism
  • Biomarkers / blood
  • Cattle
  • Cattle Diseases / parasitology*
  • Enzyme-Linked Immunosorbent Assay / veterinary
  • Escherichia coli / genetics
  • Female
  • Fluorescent Antibody Technique, Indirect
  • Glutathione Transferase / metabolism
  • Neospora / isolation & purification*
  • Pregnancy
  • Recombinant Fusion Proteins / immunology
  • Recombinant Fusion Proteins / metabolism

Substances

  • Antibodies
  • Antigens, Protozoan
  • Biomarkers
  • Recombinant Fusion Proteins
  • Glutathione Transferase