Biological Activities of Hydrazone Derivatives

Molecules. 2007 Aug 17;12(8):1910-39. doi: 10.3390/12081910.

Abstract

There has been considerable interest in the development of novel compounds with anticonvulsant, antidepressant, analgesic, antiinflammatory, antiplatelet, antimalarial, antimicrobial, antimycobacterial, antitumoral, vasodilator, antiviral and antischistosomiasis activities. Hydrazones possessing an azometine -NHN=CH- proton constitute an important class of compounds for new drug development. Therefore, many researchers have synthesized these compounds as target structures and evaluated their biological activities. These observations have been guiding for the development of new hydrazones that possess varied biological activities.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Hydrazones / chemistry*
  • Hydrazones / pharmacology*

Substances

  • Hydrazones