Moderate exercise reduces serum triacylglycerol concentrations but does not affect pre-heparin lipoprotein lipase concentrations after a moderate-fat meal in young men

Br J Nutr. 2008 May;99(5):1076-82. doi: 10.1017/S0007114507853438. Epub 2007 Oct 26.


Aerobic exercise has been shown to lower postprandial TAG concentrations after a meal(s) of high-fat content. This study examined the effects of moderate-intensity cycling on postprandial TAG concentrations and pre-heparin lipoprotein lipase concentrations after subjects consumed a meal of moderate-fat content (45 % of total energy). Twelve male subjects, aged 24 (sem 1) years, completed two 2 d trials (exercise and control) at least 1 week apart in a randomised, repeated measures design. On day 1, subjects either cycled for 30 min at 65 % of maximum heart rate in the afternoon or rested (no exercise). On day 2 of both trials, after an overnight stay with an 11 h fast, subjects consumed a test meal of moderate-fat content (0.61 g fat, 1.34 g carbohydrate, 0.37 g protein and 51 kJ energy/kg body mass) for breakfast. Blood samples were collected at baseline (before the exercise or at an equivalent time-point during the control trial on day 1), in the fasted state (0 h) and at 2, 4 and 6 h postprandially on day 2. The total and incremental areas under the serum TAG concentration v. time curve were 30 % (P = 0.039) and 33 % (P = 0.012) lower on the exercise trial compared with the control trial, respectively. Serum pre-heparin lipoprotein lipase concentrations did not differ between the exercise and control trials. These findings demonstrate that 30 min of moderate-intensity cycling performed the day before a meal of moderate-fat content is effective at lowering postprandial serum TAG concentrations but does not affect serum pre-heparin lipoprotein lipase concentrations in young men.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Glucose / metabolism
  • Dietary Fats / administration & dosage*
  • Energy Metabolism / physiology
  • Exercise / physiology*
  • Exercise Test / methods
  • Fatty Acids, Nonesterified / blood
  • Humans
  • Insulin / blood
  • Lipoprotein Lipase / blood*
  • Male
  • Postprandial Period / physiology
  • Triglycerides / blood*
  • Young Adult


  • Blood Glucose
  • Dietary Fats
  • Fatty Acids, Nonesterified
  • Insulin
  • Triglycerides
  • Lipoprotein Lipase