Stroke in Isfahan, Iran: hospital admission and 28-day case fatality rate

Cerebrovasc Dis. 2007;24(6):495-9. doi: 10.1159/000110418. Epub 2007 Oct 29.


Background: In Isfahan, a city in the middle of Iran, a community intervention trial has been started for cardiovascular disease prevention and control via reducing its risk factors and improvement of relevant healthy behavior. A surveillance system was needed to monitor vascular diseases, especially stroke, during and following this community intervention program.

Methods: A prospective study on hospitalized stroke patients was done in Isfahan, Iran, from 2000 to 2003. All hospitalized stroke events were recorded via a system adopted from the World Health Organization Monitoring Trends and Determinants in Cardiovascular Disease (MONICA) project, yet ignoring the MONICA age limitation. The age-adjusted hospital admission rate was calculated. Patients and/or their families were followed and asked regarding the patients' survival status.

Results: The age-adjusted hospital admission rate in Isfahan was increasing from 2000 to 2003 (rising from 84.16 to 103.23/100,000). The 28-day case fatality rates were nearly the same during these years and were about 32%. Ischemic stroke events made up the majority of cases (about 70%), and intracerebral hemorrhage events had the second highest prevalence (25%).

Conclusions: This study showed that the stroke hospital admission rate might be increasing in Isfahan. A community-based stroke incidence study is needed to elucidate stroke epidemiology in Isfahan, Iran, as a Middle East country.

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Brain Ischemia / complications
  • Cerebral Hemorrhage / complications
  • Female
  • Follow-Up Studies
  • Hospitalization* / statistics & numerical data
  • Humans
  • Iran / epidemiology
  • Male
  • Middle Aged
  • Prospective Studies
  • Stroke / epidemiology*
  • Stroke / etiology
  • Stroke / mortality
  • Stroke / therapy*
  • Time Factors