Valvular heart disease in the community: a European experience

Curr Probl Cardiol. 2007 Nov;32(11):609-61. doi: 10.1016/j.cpcardiol.2007.07.002.


The Euro Heart Survey on valvular heart disease included 5001 patients from 92 centers in 25 European countries in 2001: 71.9% had native valve disease and 28.1% had previously undergone valve surgery. Aortic stenosis (AS) and mitral regurgitation (MR) accounted for 43.1 and 33.6%, respectively, of single-valve diseases and were mostly caused by degenerative diseases. Mean age was 69 and 65 years, respectively, and at least one comorbidity was present in 36.3% of patients with AS and 41.7% with MR. Analysis of the therapeutic decision in patients with severe valve diseases showed that symptomatic patients were frequently denied surgery (32.3% in AS after the age of 75 and 51.3% in MR), more on the basis of age and left ventricular function than comorbidities. There was a better concordance between practice and guidelines concerning interventions in asymptomatic patients. These findings underline the need for better implementation of guidelines.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aortic Valve Stenosis / epidemiology
  • Aortic Valve Stenosis / etiology
  • Aortic Valve Stenosis / pathology
  • Aortic Valve Stenosis / therapy
  • Cardiovascular Surgical Procedures / statistics & numerical data
  • Comorbidity
  • Europe / epidemiology
  • European Continental Ancestry Group
  • Female
  • Heart Valve Diseases / epidemiology*
  • Heart Valve Diseases / etiology
  • Heart Valve Diseases / pathology
  • Heart Valve Diseases / therapy
  • Humans
  • Male
  • Middle Aged
  • Mitral Valve Insufficiency / epidemiology
  • Mitral Valve Insufficiency / etiology
  • Mitral Valve Insufficiency / pathology
  • Mitral Valve Insufficiency / therapy
  • Practice Guidelines as Topic
  • Risk Factors
  • Severity of Illness Index
  • Survival Analysis