CONSORF: a consensus prediction system for prokaryotic coding sequences

Bioinformatics. 2007 Nov 15;23(22):3088-90. doi: 10.1093/bioinformatics/btm512. Epub 2007 Oct 31.

Abstract

CONSORF is a fully automatic high-accuracy identification system that provides consensus prokaryotic CDS information. It first predicts the CDSs supported by consensus alignments. The alignments are derived from multiple genome-to-proteome comparisons with other prokaryotes using the FASTX program. Then, it fills the empty genomic regions with the CDSs supported by consensus ab initio predictions. From those consensus results, CONSORF provides prediction reliability scores, predicted frame-shifts, alternative start sites and best pair-wise match information against other prokaryotes. These results are easily accessed from a website.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Base Sequence
  • Chromosome Mapping / methods*
  • Consensus Sequence / genetics*
  • Genome, Bacterial / genetics*
  • Molecular Sequence Data
  • Open Reading Frames / genetics*
  • Sequence Alignment / methods*
  • Sequence Analysis, DNA / methods*
  • Software*