Torasemide transport by organic anion transporters contributes to hyperuricemia

J Am Soc Nephrol. 2007 Dec;18(12):3101-9. doi: 10.1681/ASN.2007010106. Epub 2007 Oct 31.
No abstract available

MeSH terms

  • Animals
  • Antihypertensive Agents / pharmacokinetics*
  • Aryl Hydrocarbon Hydroxylases / metabolism
  • Biological Transport
  • Cytochrome P-450 CYP2C9
  • Humans
  • Hyperuricemia / metabolism*
  • Kinetics
  • Models, Chemical
  • Oocytes / metabolism
  • Organic Anion Transporters / metabolism*
  • Oxygen / metabolism
  • Protein Transport
  • Sulfonamides / pharmacokinetics*
  • Torsemide
  • Transfection
  • Xenopus laevis

Substances

  • Antihypertensive Agents
  • Organic Anion Transporters
  • Sulfonamides
  • CYP2C9 protein, human
  • Cytochrome P-450 CYP2C9
  • Aryl Hydrocarbon Hydroxylases
  • Oxygen
  • Torsemide