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Review
, 17 (5), 713-8

Meta-analysis of Aggression and/or Hostility-Related Events in Children and Adolescents Treated With Fluoxetine Compared With Placebo

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Review

Meta-analysis of Aggression and/or Hostility-Related Events in Children and Adolescents Treated With Fluoxetine Compared With Placebo

Sitra Tauscher-Wisniewski et al. J Child Adolesc Psychopharmacol.

Abstract

This meta-analysis assessed aggression and/or hostility-related events in children and adolescents treated with fluoxetine (n = 376) compared with placebo (n = 255). Aggression and/or hostility-related events were identified in 2.1% of fluoxetine versus 3.1% of placebo-treated patients (p = 0.588). This analysis fails to support an association between fluoxetine treatment and increased risk of aggression and/or hostility-related events in children and adolescents compared with placebo.

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