The contraceptive implant

Clin Obstet Gynecol. 2007 Dec;50(4):907-17. doi: 10.1097/GRF.0b013e318159c2f6.


Contraceptive implants provide long-acting, highly effective reversible contraception. Currently, the only subdermal implant available to women in the United States is the single rod etonogestrel implant, Implanon (N.V. Organon, Oss, the Netherlands) approved by the Food and Drug Administration in July 2006. Implanon is currently approved for 3 years of use, provides excellent efficacy throughout its use, and is easy to insert and remove. Similar to other progestin-only contraceptives, Implanon can cause irregular vaginal bleeding. Implanon has been shown to be safe to use during lactation, may improve dysmenorrhea, and does not significantly affect bone mineral density, lipid profile, or liver enzymes.

Publication types

  • Review

MeSH terms

  • Acne Vulgaris / chemically induced
  • Acne Vulgaris / epidemiology
  • Bone Density / drug effects
  • Contraception / methods*
  • Contraceptive Agents, Female / adverse effects*
  • Contraceptive Agents, Female / pharmacology*
  • Device Removal
  • Drug Implants
  • Female
  • Humans
  • Lipid Metabolism / drug effects
  • Liver / drug effects
  • Liver / physiology
  • Menstruation Disturbances / chemically induced
  • Menstruation Disturbances / epidemiology
  • Ovarian Cysts / chemically induced
  • Ovarian Cysts / epidemiology
  • Patient Satisfaction
  • Safety*
  • Time Factors


  • Contraceptive Agents, Female
  • Drug Implants