The transdermal contraceptive patch: an updated review of the literature

Clin Obstet Gynecol. 2007 Dec;50(4):918-26. doi: 10.1097/GRF.0b013e318159c410.

Abstract

The transdermal contraceptive patch which contains ethinyl estradiol and norelgestromin has an efficacy similar to current oral contraceptives (OCs). The major advantages include transdermal application and maintenance of adequate hormonal levels for at least 7 days. Side effects are similar to OC except for breast tenderness in the first 2 months of use and skin irritation at the application site. Although concern has been raised about a possible increased risk of venous thromboembolism, current available data comparing the patch to a norgestimate-containing OC ranges from no increase in risk to a 2.4-fold increase.

Publication types

  • Review

MeSH terms

  • Administration, Cutaneous
  • Adolescent
  • Adult
  • Age Factors
  • Body Weight / drug effects*
  • Contraceptive Agents, Female / adverse effects*
  • Contraceptive Agents, Female / pharmacology*
  • Contraceptives, Oral, Combined
  • Contraceptives, Oral, Synthetic
  • Drug Implants
  • Female
  • Humans
  • Menstrual Cycle / drug effects*
  • Patient Compliance
  • Risk Factors
  • Thromboembolism / chemically induced
  • Thromboembolism / epidemiology

Substances

  • Contraceptive Agents, Female
  • Contraceptives, Oral, Combined
  • Contraceptives, Oral, Synthetic
  • Drug Implants