Modern management of pheochromocytoma

Nat Clin Pract Urol. 2007 Nov;4(11):630-3. doi: 10.1038/ncpuro0962.

Abstract

Background: A 55-year-old male with poorly controlled hypertension and a history of coronary artery disease presented with a large adrenal mass. The patient also reported a long-standing history of profuse sweating, tinnitus, vomiting and headaches.

Investigations: Physical examination, 24-hour urine metanephrine level, CT, MRI and bone scan.

Diagnosis: Pheochromocytoma of the left adrenal gland.

Management: Preoperative alpha-blockade therapy with phenoxybenzamine followed by open left adrenalectomy.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adrenal Gland Neoplasms / diagnosis
  • Adrenal Gland Neoplasms / therapy*
  • Adrenalectomy
  • Adrenergic alpha-Antagonists / therapeutic use
  • Combined Modality Therapy
  • Diagnosis, Differential
  • Humans
  • Male
  • Metanephrine / blood
  • Middle Aged
  • Phenoxybenzamine / therapeutic use
  • Pheochromocytoma / diagnosis
  • Pheochromocytoma / therapy*

Substances

  • Adrenergic alpha-Antagonists
  • Phenoxybenzamine
  • Metanephrine