AMPK and SNF1: Snuffing Out Stress

Cell Metab. 2007 Nov;6(5):339-40. doi: 10.1016/j.cmet.2007.10.001.


AMP-activated protein kinase (AMPK) has attracted much attention for its key role in energy homeostasis. Three new papers providing structural information on mammalian and yeast AMPK homologs give insights into the binding of the regulatory nucleotides AMP and ATP and how mutations are associated with cardiac glycogen storage disorders.

Publication types

  • Editorial

MeSH terms

  • AMP-Activated Protein Kinases
  • Animals
  • Humans
  • Models, Molecular
  • Multienzyme Complexes / chemistry*
  • Multienzyme Complexes / metabolism*
  • Phosphorylation
  • Protein Structure, Secondary
  • Protein-Serine-Threonine Kinases / chemistry*
  • Protein-Serine-Threonine Kinases / metabolism*


  • Multienzyme Complexes
  • SNF1-related protein kinases
  • Protein-Serine-Threonine Kinases
  • AMP-Activated Protein Kinases