The Gene Ontology project in 2008

Nucleic Acids Res. 2008 Jan;36(Database issue):D440-4. doi: 10.1093/nar/gkm883. Epub 2007 Nov 4.


The Gene Ontology (GO) project ( provides a set of structured, controlled vocabularies for community use in annotating genes, gene products and sequences (also see The ontologies have been extended and refined for several biological areas, and improvements to the structure of the ontologies have been implemented. To improve the quantity and quality of gene product annotations available from its public repository, the GO Consortium has launched a focused effort to provide comprehensive and detailed annotation of orthologous genes across a number of 'reference' genomes, including human and several key model organisms. Software developments include two releases of the ontology-editing tool OBO-Edit, and improvements to the AmiGO browser interface.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Databases, Genetic* / standards
  • Genomics
  • Humans
  • Internet
  • Mice
  • Rats
  • Sequence Analysis
  • User-Computer Interface
  • Vocabulary, Controlled*