[Cutaneous inflammatory pseudotumor (plasmocytoid granuloma)]

Pathologica. 2007 Jun;99(3):84-6.
[Article in Italian]

Abstract

Cutaneous inflammatory pseudotumor is a rare benign condition that should be macroscopically differentiated, from dermatofibroma and metastases of carcinoma and, histologically from cutaneous lymphomas and other more aggressive diseases. We report herein the case of a 63-year-old man with a painless nodule of the left arm skin with a rapid growth (1 month ago). The histological examination revealed a well-defined dermal nodule of plasmacytoid cells, without connection or infiltration of the epidermis. At high power the polymorphous cellular infiltrate was, constituted by medium- small elements with widespread features of lympho-plasmocytoid differentiation or clear plasmacellular features. Immunohistochemical analysis showed a polyclonal cytological pattern with expression of both immunoglobulin light chains kappa e lambda by plasmacytoid and admixed B and T lymphocytes. The final diagnosis was Plasmocytoid granuloma an entity that is recognized within the so called "Cutaneous inflammatory pseudotumor" together with the myofibroblastic tumor.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Arm*
  • B-Lymphocytes
  • Granuloma, Plasma Cell / pathology*
  • Granuloma, Plasma Cell / surgery
  • Humans
  • Inflammation
  • Male
  • Middle Aged
  • Skin Diseases / pathology*
  • Skin Diseases / surgery
  • T-Lymphocytes