Bacillamides from a hypersaline microbial mat bacterium

J Nat Prod. 2007 Nov;70(11):1793-5. doi: 10.1021/np070126a. Epub 2007 Nov 8.

Abstract

Chemical studies of a Bacillus endophyticus isolated from a Bahamian hypersaline microbial mat led to the isolation of bacillamides B and C, new tryptamide thiazole metabolites. Bioassay-guided fractionation using a HPLC-UV-MS bioassay technique enabled the detection of these trace fermentation products, and their total structures were elucidated by combined spectroscopic techniques.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Bacillus / chemistry*
  • Bahamas
  • Chromatography, High Pressure Liquid
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Thiazoles / chemistry
  • Thiazoles / isolation & purification*
  • Tryptamines / chemistry
  • Tryptamines / isolation & purification*
  • Water Microbiology*

Substances

  • Thiazoles
  • Tryptamines
  • bacillamide B
  • bacillamide C