Randomized trials to optimize treatment of multidrug-resistant tuberculosis

PLoS Med. 2007 Nov 6;4(11):e292. doi: 10.1371/journal.pmed.0040292.


The time is now right for randomized trials of MDR-TB, say the authors, as the expansion of MDR-TB programs provides the setting in which trials can be implemented.

MeSH terms

  • Antitubercular Agents / therapeutic use*
  • Extensively Drug-Resistant Tuberculosis / drug therapy*
  • Extensively Drug-Resistant Tuberculosis / microbiology
  • Fluoroquinolones / therapeutic use
  • Humans
  • Mycobacterium tuberculosis
  • Randomized Controlled Trials as Topic
  • Tuberculosis, Multidrug-Resistant / drug therapy*
  • Tuberculosis, Multidrug-Resistant / microbiology


  • Antitubercular Agents
  • Fluoroquinolones