Monoterpene glycosides isolated from Fadogia agrestis

Phytochemistry. 2008 Feb;69(3):805-11. doi: 10.1016/j.phytochem.2007.09.024. Epub 2007 Nov 7.


Six monoterpene glycosides were isolated from Fadogia agrestis. Their structures were elucidated using a combination of mass spectroscopy, 1D- and 2D-homo- and hetero-NMR spectroscopy and chemical analysis, and established as being derivatives of 2,6-dimethyl-2(E),6(Z)-octadiene-1,8-diol containing from two to four units of rhamnopyranose and, three of them, one or two additional units of glucopyranose. In three of the compounds an acyl group of 8-hydroxy-2,6-dimethyl-2(E),6(Z)-octadienoyl was found esterifying the O-2 position of one of the units of rhamnopyranose.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Magnetic Resonance Spectroscopy / methods
  • Magnetic Resonance Spectroscopy / standards
  • Mass Spectrometry / methods
  • Molecular Conformation
  • Monoterpenes / chemistry
  • Monoterpenes / isolation & purification*
  • Reference Standards
  • Rubiaceae / chemistry*
  • Stereoisomerism


  • Glycosides
  • Monoterpenes