Organ allocation in lung transplant

Chest. 2007 Nov;132(5):1646-51. doi: 10.1378/chest.07-0011.


Since the first successful single-lung transplant in 1983 and double-lung transplant in 1986, thousands of patients have benefited from the procedures. Until 1995, allocation of donor lungs was based purely on time on the waiting list. In 1995, a 90-day credit was given to patients with idiopathic pulmonary fibrosis, while still maintaining allocation based on waiting list time. In 2005, the lung allocation score (LAS) was implemented, dramatically changing the way lungs are allocated. This article will explore the reasons for the creation of the LAS, the design of the score, early experience with transplant results under the new system, and further changes that may be made to the system of lung allocation. As surgical techniques and medical management evolve, so to will the management of potential donors and the allocation of their organs, with the aim of benefiting patients needing lung transplantation in the United States.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Humans
  • Lung Transplantation / statistics & numerical data*
  • Lung Transplantation / trends
  • Risk Factors
  • Survival Analysis
  • Time Factors
  • Tissue and Organ Procurement / statistics & numerical data*
  • Tissue and Organ Procurement / trends
  • United States / epidemiology
  • Waiting Lists