Malignant astrocytoma following radiotherapy for craniopharyngioma

J Cancer Res Ther. 2007 Jan-Mar;3(1):50-2. doi: 10.4103/0973-1482.31974.


Radiation induced gliomas are uncommon. Occurrence of glioma following radiotherapy for craniopharyngiomas is extremely uncommon and only eight case reports have been so far published. We present our experience with one similar case of temporal gliomas occurring twelve years following radiotherapy for a sub totally excised craniopharyngioma. Although the exact mechanism of gliomas formation is unclear, their occurrence following conventional radiotherapy is a distinct possibility and signifies a poor prognosis.

Publication types

  • Case Reports

MeSH terms

  • Astrocytoma / etiology*
  • Astrocytoma / surgery
  • Brain Neoplasms / etiology*
  • Child, Preschool
  • Craniopharyngioma / radiotherapy*
  • Humans
  • Male
  • Neoplasms, Radiation-Induced / etiology*
  • Pituitary Neoplasms / radiotherapy*
  • Radiotherapy / adverse effects*