A Brain Implantable Microsystem With Hybrid RF/IR Telemetry for Advanced Neuroengineering Applications

Conf Proc IEEE Eng Med Biol Soc. 2007;2007:445-8. doi: 10.1109/IEMBS.2007.4352319.


A prototype cortical neural interface microsystem has been developed for brain implantable neuroengineering applications, featuring hybrid RF (radio-frequency) inductive and IR (infrared) optical telemetries. The system is aimed at neural recording from primates by converting cortical signals to a digital stream of IR light pulses, while acquiring clock signal and electrical power through RF induction. The implantable unit employs a flexible LCP (liquid crystal polymer) substrate for integration of analog, digital, and optoelectronic components, while adapting to the anatomical and physiological constraints of the environment. An ultra-low power analog CMOS chip, which includes preamplifier and multiplexing circuitry, is directly flip-chip bonded to the microelectrode array to form the immediate cortical neuroprobe device. A 16-channel version of the probe has been tested in various in-vivo animal experiments, including measurements of neural activity in somatosensory cortex of a rat.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Cerebral Cortex*
  • Humans
  • Infrared Rays*
  • Liquid Crystals
  • Polymers
  • Prostheses and Implants*
  • Radio Waves*
  • Rats
  • Signal Transduction*
  • Telemetry / instrumentation*
  • Telemetry / methods


  • Polymers
  • liquid crystal polymer