Use of Ni electrodes chronoamperometry for improved diagnostics of diabetes and cardiac diseases

Annu Int Conf IEEE Eng Med Biol Soc. 2007;2007:4544-7. doi: 10.1109/IEMBS.2007.4353350.


Low DC active current through Nickel electrodes applied on skin in places like hands, forehead and feet provides a novel non invasive diagnostic tool using reverse iontophoresis. This work describes the electrochemistry reactions involved and some medical applications, such as diagnostics of neuropathy, diabetes and cardiac diseases. Finally we provide evidence for the utility of this method through large clinical studies.

MeSH terms

  • Diabetes Mellitus / diagnosis*
  • Electric Impedance*
  • Heart Diseases / diagnosis*
  • Humans
  • Iontophoresis / methods*
  • Reproducibility of Results