CuCl2-catalyzed one-pot formation of tetrahydroquinolines from N-methyl-N-alkylanilines and vinyl ethers in the presence of t-butylhydroperoxide

Xianghua Yang; Chanjuan Xi; Yanfeng Jiang

doi:10.3390/11120978

CuCl2-catalyzed one-pot formation of tetrahydroquinolines from N-methyl-N-alkylanilines and vinyl ethers in the presence of t-butylhydroperoxide

Molecules. 2006 Dec 20;11(12):978-87. doi: 10.3390/11120978.

Authors

Xianghua Yang¹, Chanjuan Xi, Yanfeng Jiang

Affiliation

¹ Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, PR China. yxh04@mails.tsinghua.edu.cn

Abstract

Tetrahydroquinoline skeletons can be formed by a CuCl2-catalyzed one-pot reaction of N-methyl-N-alkylanilines and vinyl ethers in the presence of t-butyl-hydroperoxide.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aniline Compounds / chemistry*
Catalysis
Chemistry Techniques, Analytical / methods*
Copper / chemistry*
Quinolines / chemical synthesis*
Vinyl Compounds / chemistry*
tert-Butylhydroperoxide / chemistry*

Substances

Aniline Compounds
Quinolines
Vinyl Compounds
vinyl ether
Copper
tert-Butylhydroperoxide
cupric chloride