Acute myocardial infarction related to methylphenidate for adult attention deficit disorder

J Emerg Med. 2010 Jan;38(1):18-21. doi: 10.1016/j.jemermed.2007.06.021. Epub 2007 Nov 19.


Adult Attention Deficit Disorder is increasingly diagnosed and treated. Psychostimulant medications, such as methylphenidate, are commonly prescribed for this condition, but the long-term safety of such medications in an adult population is unknown at present. Because these medications are closely related to amphetamines, it is expected that toxic side effects would be similar. We present the case of a 27-year-old man who suffered an acute myocardial infarction due to coronary vasospasm related to use of methylphenidate complicated by concomitant use of pseudoephedrine.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Attention Deficit Disorder with Hyperactivity / drug therapy*
  • Central Nervous System Stimulants / adverse effects*
  • Coronary Vasospasm / chemically induced*
  • Humans
  • Male
  • Methylphenidate / adverse effects*
  • Myocardial Infarction / chemically induced*


  • Central Nervous System Stimulants
  • Methylphenidate