Antibiotic resistance and resistance mechanisms in Campylobacter jejuni and Campylobacter coli

FEMS Microbiol Lett. 2007 Dec;277(2):123-32. doi: 10.1111/j.1574-6968.2007.00935.x.


Campylobacter jejuni and Campylobacter coli are recognized as the most common causative agents of bacterial gastroenteritis in the world and infections with these organisms occur more frequently than do infections due to Salmonella species, Shigella species, or Escherichia coli 0157:H7. The incidence of human Campylobacter infections has increased markedly in both developed and developing countries worldwide and, more significantly, so has the rapid emergence of antibiotic-resistant Campylobacter strains, with evidence suggesting that the use of antibiotics, in particular the fluoroquinolones, as growth promoters in food animals and the veterinary industry is accelerating this trend. In this minireview, the patterns of emerging resistance to the antimicrobial agents useful in treatment of the disease are presented and the mechanisms of resistance to these drugs in Campylobacter spp are discussed.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / metabolism
  • Anti-Bacterial Agents / pharmacology*
  • Campylobacter coli / drug effects*
  • Campylobacter coli / genetics
  • Campylobacter jejuni / drug effects*
  • Campylobacter jejuni / genetics
  • Drug Resistance, Bacterial / genetics*
  • Drug Resistance, Bacterial / physiology*


  • Anti-Bacterial Agents