The genomic and metabolic diversity of Rickettsia

Res Microbiol. 2007 Dec;158(10):745-53. doi: 10.1016/j.resmic.2007.09.008. Epub 2007 Oct 4.

Abstract

Comparative genomics of Rickettsia and Orientia has revealed an exciting interplay between reductive evolutionary forces acting on metabolic genes in all species and proliferation of mobile genetic elements in some species. These contradictory evolutionary forces highlight the influence of chance, adaptation and host-cell exploitation during the evolution of intracellular bacteria.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Evolution, Molecular
  • Genome, Bacterial*
  • Genomic Instability
  • Host-Pathogen Interactions
  • Humans
  • Orientia tsutsugamushi / genetics
  • Orientia tsutsugamushi / pathogenicity
  • Rickettsia / genetics*
  • Rickettsia / metabolism*
  • Rickettsia / pathogenicity
  • Rickettsia Infections / genetics
  • Rickettsia prowazekii / genetics
  • Rickettsia prowazekii / pathogenicity
  • Typhus, Epidemic Louse-Borne / microbiology