A potential role for the hippocampus in energy intake and body weight regulation

Curr Opin Pharmacol. 2007 Dec;7(6):613-6. doi: 10.1016/j.coph.2007.10.008. Epub 2007 Nov 26.


Recent research and theory point to the possibility that hippocampal-dependent learning and memory mechanisms translate neurohormonal signals of energy balance into adaptive behavioral outcomes involved with the inhibition of food intake. The present paper summarizes these findings and ideas and considers the hypothesis that excessive caloric intake and obesity may be produced by dietary and other factors that are known to alter hippocampal functioning.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Animals
  • Body Weight / physiology*
  • Energy Intake / physiology*
  • Hippocampus / physiology*
  • Hippocampus / physiopathology
  • Humans
  • Obesity / physiopathology