The DNA transposon Minos as a tool for transgenesis and functional genomic analysis in vertebrates and invertebrates

Genome Biol. 2007;8 Suppl 1(Suppl 1):S2. doi: 10.1186/gb-2007-8-s1-s2.

Abstract

Transposons are powerful tools for conducting genetic manipulation and functional studies in organisms that are of scientific, economic, or medical interest. Minos, a member of the Tc1/mariner family of DNA transposons, exhibits a low insertional bias and transposes with high frequency in vertebrates and invertebrates. Its use as a tool for transgenesis and genome analysis of rather different animal species is described.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • DNA Transposable Elements / genetics*
  • Gene Transfer Techniques*
  • Genomics / methods*
  • Invertebrates / genetics*
  • Vertebrates / genetics*

Substances

  • DNA Transposable Elements