Geodesic-loxodromes for diffusion tensor interpolation and difference measurement

Med Image Comput Comput Assist Interv. 2007;10(Pt 1):1-9. doi: 10.1007/978-3-540-75757-3_1.

Abstract

In algorithms for processing diffusion tensor images, two common ingredients are interpolating tensors, and measuring the distance between them. We propose a new class of interpolation paths for tensors, termed geodesic-loxodromes, which explicitly preserve clinically important tensor attributes, such as mean diffusivity or fractional anisotropy, while using basic differential geometry to interpolate tensor orientation. This contrasts with previous Riemannian and Log-Euclidean methods that preserve the determinant. Path integrals of tangents of geodesic-loxodromes generate novel measures of over-all difference between two tensors, and of difference in shape and in orientation.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Algorithms*
  • Brain / anatomy & histology*
  • Computer Simulation
  • Diffusion Magnetic Resonance Imaging / methods*
  • Humans
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / methods*
  • Models, Biological
  • Numerical Analysis, Computer-Assisted
  • Reproducibility of Results
  • Sensitivity and Specificity