Posterior error probabilities and false discovery rates: two sides of the same coin

J Proteome Res. 2008 Jan;7(1):40-4. doi: 10.1021/pr700739d. Epub 2007 Dec 4.


A variety of methods have been described in the literature for assigning statistical significance to peptides identified via tandem mass spectrometry. Here, we explain how two types of scores, the q-value and the posterior error probability, are related and complementary to one another.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Algorithms
  • Databases, Protein
  • Models, Statistical*
  • Peptides / analysis*
  • Tandem Mass Spectrometry / methods*


  • Peptides