Platinum-catalyzed regio- and stereoselective arylthiolation of internal alkynes

Fumikazu Yamashita; Hitoshi Kuniyasu; Jun Terao; Nobuaki Kambe

doi:10.1021/ol7025069

Platinum-catalyzed regio- and stereoselective arylthiolation of internal alkynes

Org Lett. 2008 Jan 3;10(1):101-4. doi: 10.1021/ol7025069. Epub 2007 Dec 4.

Authors

Fumikazu Yamashita¹, Hitoshi Kuniyasu, Jun Terao, Nobuaki Kambe

Affiliation

¹ Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.

PMID: 18052182
DOI: 10.1021/ol7025069

Abstract

Unsymmetrical internal alkynes such as ethyl phenylpropiolate (2b) successfully underwent Pt-catalyzed decarbonylative arylthiolation by thioesters. The regio- and stereoselective insertion of 2b into an S-Pt bond was confirmed by reaction with a platinum complex with an S-Pt-Cl framework.