Increasing folate supplementation for selected groups of Canadian women

J Obstet Gynaecol Can. 2007 Dec;29(12):992-996. doi: 10.1016/S1701-2163(16)32690-1.


After review of current evidence related to the potential risks and benefits of folic acid supplementation, we conclude that unless clinicians can be assured that pregnant women will reliably use prenatal vitamin supplements containing 0.8-1.1 mg of folate, the prenatal vitamin supplements should be combined with 5 mg of folate.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Canada
  • Dietary Supplements*
  • Female
  • Folic Acid / administration & dosage*
  • Humans
  • Neural Tube Defects / prevention & control*
  • Nutritional Requirements
  • Pregnancy
  • Pregnancy Complications / prevention & control*
  • Vitamin B Complex / administration & dosage*


  • Vitamin B Complex
  • Folic Acid