Gaining and losing the thermophilic adaptation in prokaryotes

Trends Genet. 2008 Jan;24(1):10-4. doi: 10.1016/j.tig.2007.10.005. Epub 2007 Dec 3.


We studied the evolution of thermophily in prokaryotes using the phylogenetic relationships between 279 bacteria and archaea and their thermophilic amino acid composition signature. Our findings suggest several examples in which the capacity of thermophilic adaptation has been gained or lost over relatively short evolutionary periods throughout the evolution of prokaryotes.

MeSH terms

  • Adaptation, Physiological*
  • Amino Acids
  • Phylogeny
  • Prokaryotic Cells / metabolism*
  • Proteome / chemistry
  • Temperature*


  • Amino Acids
  • Proteome