Delusion formation and reasoning biases in those at clinical high risk for psychosis

Br J Psychiatry Suppl. 2007 Dec:51:s38-42. doi: 10.1192/bjp.191.51.s38.

Abstract

Background: Cognitive models propose that faulty appraisal of anomalous experiences is critical in developing psychosis, particularly delusions. A data gathering bias may be fundamental to abnormal appraisal.

Aims: To examine whether there is a data gathering bias in people at high risk of developing psychosis.

Method: Individuals with an at-risk mental state (n=35) were compared with a matched group of healthy volunteers (n=23). Participants were tested using a modified version of the 'beads' reasoning task with different levels of task difficulty.

Results: When task demands were high, the at-risk group made judgements on the basis of less information than the control group (P<0.05). Within both groups, jumping to conclusions was directly correlated with the severity of abnormal beliefs and intolerance of uncertainty (P<0.05). In the at-risk group it was also associated with impaired working memory (P<0.05), whereas in the control group poor working memory was associated with a more conservative response style (P<0.05).

Conclusions: People with an at-risk mental state display a jumping to conclusions reasoning style, associated with impaired working memory and intolerance of uncertainty. This may underlie a tendency to develop abnormal beliefs and a vulnerability to psychosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Delusions / etiology*
  • Delusions / psychology
  • Humans
  • Impulsive Behavior / psychology
  • Intelligence
  • Judgment*
  • Memory, Short-Term
  • Neuropsychological Tests
  • Problem Solving
  • Psychiatric Status Rating Scales
  • Psychotic Disorders / psychology*