Evaluation of genetic markers linked to hemophilia A locus: an Indian experience

Haematologica. 2007 Dec;92(12):1725-6. doi: 10.3324/haematol.11545.


Hemophilia A is an X-linked recessive bleeding disorder caused by defects in factor VIII gene (F8). Our study examines variations of single nucleotide polymorphism (SNP) in F8 in the Indian population and establishes the utility of a combination of SNP and microsatellite markers for the successful identification of carriers in the affected families.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Evaluation Studies as Topic
  • Female
  • Genetic Carrier Screening
  • Genetic Markers
  • Hemophilia A / genetics*
  • Humans
  • India
  • Male
  • Microsatellite Repeats / genetics*
  • Polymorphism, Single Nucleotide*
  • Quantitative Trait Loci / genetics*


  • Genetic Markers