Inhibition of fracture healing

J Bone Joint Surg Br. 2007 Dec;89(12):1553-60. doi: 10.1302/0301-620X.89B12.19671.


This paper reviews the current literature concerning the main clinical factors which can impair the healing of fractures and makes recommendations on avoiding or minimising these in order to optimise the outcome for patients. The clinical implications are described.

Publication types

  • Review

MeSH terms

  • Alcoholism / physiopathology
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology
  • Diabetes Mellitus / physiopathology
  • Fracture Healing* / drug effects
  • Glucocorticoids / pharmacology
  • Humans
  • Smoking / physiopathology


  • Anti-Inflammatory Agents, Non-Steroidal
  • Glucocorticoids