Endonasal transsphenoidal pituitary surgery: is tumor volume a key factor in determining outcome?

Am J Otolaryngol. 2008 Jan-Feb;29(1):48-50. doi: 10.1016/j.amjoto.2007.01.006.

Abstract

Purpose: This study was conducted to evaluate the role of tumor volume in excision of pituitary adenomas.

Materials and methods: A total of 20 patients with pituitary adenoma underwent surgical excision of the tumor by endonasal transsphenoidal approach.

Results: A preoperative tumor volume of more than 5 mL is associated with a 90.90% probability of residual tumor (P < .05, statistically significant).

Conclusion: Tumor volume as a predicting factor for the surgical outcome is an evolving concept. Other factors determining the efficacy of tumor removal are parasellar and suprasellar extension.

MeSH terms

  • Adenoma / diagnostic imaging
  • Adenoma / pathology
  • Adenoma / surgery*
  • Adolescent
  • Adult
  • Endoscopy / methods*
  • Female
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Nose
  • Organ Size
  • Pituitary Neoplasms / diagnostic imaging
  • Pituitary Neoplasms / pathology
  • Pituitary Neoplasms / surgery*
  • Prospective Studies
  • Sphenoid Bone / surgery*
  • Tomography, X-Ray Computed / methods*
  • Treatment Outcome