Interpleural versus epidural analgesia with ropivacaine for postthoracotomy pain and respiratory function

J Clin Anesth. 2007 Nov;19(7):506-11. doi: 10.1016/j.jclinane.2007.04.005.

Abstract

Study objective: To evaluate the impact of interpleural analgesia (IP) on postthoracotomy pain and respiratory function as an alternative to thoracic epidural analgesia (TEA).

Design: Prospective, randomized study.

Setting: Tertiary-care military hospital.

Patients: Sixty young patients scheduled for elective thoracic surgery (correction of aorta coarctation and patent ductus arteriosus).

Interventions: Patients were randomized into two groups to receive either IP or TEA for postthoracotomy pain management.

Measurements: Patients in the IP group (n = 30) had a catheter inserted between the parietal and visceral pleura by a surgeon, and 0.2% ropivacaine was given through this catheter. In the TEA group, ropivacaine was administered through a thoracic epidural catheter. The impact of both methods on pain control, respiratory function, and pulmonary complications was analyzed and compared.

Main results: The frequency of atelectasis and pleural effusion was also significantly high in the IP group (P < 0.01). Respiratory function and postoperative pain scores were better in the TEA group (P < 0.01). Arterial blood gas analysis on the fifth postoperative day was significantly better in the TEA group.

Conclusion: Thoracic epidural analgesia has more beneficial effects on respiratory function and postoperative pain after thoracotomy than does IP.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Amides / administration & dosage*
  • Amides / adverse effects
  • Amides / therapeutic use*
  • Analgesia* / adverse effects
  • Analgesia, Epidural* / adverse effects
  • Anesthetics, Local / administration & dosage*
  • Anesthetics, Local / adverse effects
  • Anesthetics, Local / therapeutic use*
  • Aortic Coarctation / surgery
  • Blood Gas Analysis
  • Ductus Arteriosus, Patent / surgery
  • Female
  • Hospitals, Military
  • Humans
  • Injections
  • Male
  • Pain Measurement
  • Pain, Postoperative / drug therapy*
  • Pleura
  • Pleural Effusion / epidemiology
  • Pleural Effusion / etiology
  • Prospective Studies
  • Pulmonary Atelectasis / epidemiology
  • Pulmonary Atelectasis / etiology
  • Respiratory Function Tests
  • Ropivacaine
  • Thoracotomy*

Substances

  • Amides
  • Anesthetics, Local
  • Ropivacaine