Yellow nail syndrome in association with carcinoma of the gall bladder

Clin Exp Dermatol. 1991 Nov;16(6):471-3. doi: 10.1111/j.1365-2230.1991.tb01240.x.


We report the case of a 54-year-old female who was found to have adenocarcinoma of the gall bladder 2 years after the onset of yellow discolouration and deformity of all 20 nails. She also exhibited a past history of chronic sinusitis and mild bronchiectasis. As the tumour was inoperable, palliative surgery was performed. This case adds further support to a possible association between malignancy and the yellow nail syndrome (YNS).

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma / complications*
  • Female
  • Gallbladder Neoplasms / complications*
  • Humans
  • Middle Aged
  • Nail Diseases / complications*
  • Nails, Malformed / complications
  • Pigmentation Disorders / complications*
  • Syndrome