[The importance of screening for thyroid dysfunction during pregnancy: pathophysiological background and practical implications]

Cas Lek Cesk. 2007;146(11):827-33.
[Article in Czech]


Thyroid hormones are essential both for the physiological course of pregnancy and for the optimal differentiation of the embryonic tissues and foetal brain development. Overt and subclinical hypothyroidism constitutes a frequent cause of infertility, it carries along an increased risk of spontaneous abortion and premature birth, and it may lead to an impaired foetal brain development resulting in a worse psychoneurological outcome in the progeny. The repeatedly documented high prevalence of thyroid diseases in pregnancy warrants a realization of systematic screening for thyroid dysfunction during early stage of pregnancy or better before conception whenever possible. The Czech Endocrine Society attempts to implement such a systematic screening in the Czech Republic, although the particular aspects of the screening are still discussed.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Female
  • Humans
  • Hyperthyroidism / complications
  • Hyperthyroidism / diagnosis
  • Hypothyroidism / complications
  • Hypothyroidism / diagnosis
  • Pregnancy
  • Pregnancy Complications / diagnosis*
  • Thyroid Diseases / complications
  • Thyroid Diseases / diagnosis*