Objective: To evaluate the clinical effect of acellular dermal matrix (ADM) on preventing Frey syndrome after parotidectomy.
Methods: Fifty-seven patients were randomized into two groups, ADM group (30 patients) receiving acellular dermal matrix and control group (27 patients) without application of acellular dermal matrix. The incidence of Frey syndrome was evaluated after operation.
Results: The incidences of Frey syndrome were 13.3% in ADM group and 55.6% in control group. There was significant difference in Frey syndrome incidence between the two groups (P < 0.01).
Conclusions: The application of acellular dermal matrix could effectively prevent Frey syndrome after parotidectomy.