Abstract
In this study, the tet(W) gene region of a human clinical isolate of Clostridium difficile resistant to tetracycline was characterized. This gene was a new allele showing 99% sequence identity to the gene found in the human strain Bifidobacterium longum F8, and it is not transferable by "in vitro" mating experiments.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Bacterial Proteins / genetics*
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Bacterial Proteins / metabolism
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Child, Preschool
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Clostridioides difficile / drug effects*
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Clostridioides difficile / genetics
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Clostridioides difficile / pathogenicity
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DNA, Bacterial / analysis
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Enterocolitis, Pseudomembranous / microbiology
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Humans
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Phylogeny
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Sequence Analysis, DNA
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Tetracycline / pharmacology
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Tetracycline Resistance / genetics*
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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DNA, Bacterial
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Tetracycline