[Comparison of neuroprotective properties of nootropes, calcium channel blockers, and panangin]

Abstract

Neuroprotective properties of a series of drugs including nootropes, calcium channel antagonists, and panangin have been studied on a model of craniocerebral trauma. It is established that beglimin and nooglutil exhibit a moderate antiischemic, antihypoxic, and antiamnesic action in posttraumatic period; panangin possesses antiischemic, anticonvulsant, and antiamnesic properties; while nimodipin exhibit only antiamnesic action. It is concluded that beglimin, nooglutil and panangin are of importance in the pharmacological treatment of secondary traumatic brain injury.