Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2007 Dec 13;450(7172):991-1000.
doi: 10.1038/nature06525.

The Biological Impact of Mass-Spectrometry-Based Proteomics

Affiliations
Review

The Biological Impact of Mass-Spectrometry-Based Proteomics

Benjamin F Cravatt et al. Nature. .

Abstract

In the past decade, there have been remarkable advances in proteomic technologies. Mass spectrometry has emerged as the preferred method for in-depth characterization of the protein components of biological systems. Using mass spectrometry, key insights into the composition, regulation and function of molecular complexes and pathways have been gained. From these studies, it is clear that mass-spectrometry-based proteomics is now a powerful 'hypothesis-generating engine' that, when combined with complementary molecular, cellular and pharmacological techniques, provides a framework for translating large data sets into an understanding of complex biological processes.

Similar articles

See all similar articles

Cited by 206 articles

See all "Cited by" articles

Publication types

Substances

LinkOut - more resources

Feedback