Factors influencing depressive symptoms of children treated for a brain tumor

J Psychosoc Oncol. 2008;26(1):1-16. doi: 10.1300/j077v26n01_01.


Objectives: To examine depressive symptoms in children treated for a brain tumor and related clinical, demographic and personal factors.

Methods: Fifty-four children with brain tumors (32 males) aged 8.2-18.3 years participated. Standardized measures assessed depressive symptoms, social skills, self-worth and IQ. Clinical (treatment) and demographic variables (gender) were also examined.

Results: Depression scores were subjected to a 2 (gender), X 2 (social skills: low, high), X 3 (self-worth: low, average, high) ANCOVA with IQ as the covariate. Significant main effects of gender and of self-worth and an interaction between gender, social skills, and self-worth were observed. Gender was identified as a moderator of the effect of social skills and self-worth on depressive symptoms.

Conclusions: Gender, social skills, and self-worth play important roles in the depressive symptoms of pediatric brain tumor patients.

MeSH terms

  • Adolescent
  • Analysis of Variance
  • Brain Neoplasms / psychology*
  • Child
  • Depressive Disorder / etiology
  • Depressive Disorder / prevention & control*
  • Depressive Disorder / psychology
  • Female
  • Humans
  • Male
  • Risk Factors
  • Self Concept*
  • Sex Factors
  • Social Adjustment*