Recurrent sarcoidosis on a scar associated with vitiligo

J Dermatol. 2007 Dec;34(12):829-33. doi: 10.1111/j.1346-8138.2007.00394.x.

Abstract

We report a case of systemic sarcoidosis, diagnosed 13 years ago by transbronchial biopsy. Our patient had a spontaneous resolution of hilar and mediastinal lymphadenopathy 6 months after diagnosis. She presented with a skin rash on her thyroidectomy scar after a period of 4 years of complete remission. The patient complained that her thyroidectomy incision scar rose up, reddened and hardened. Biopsy of the skin lesion revealed non-caseating epithelioid granulomas with histiocytes and multinucleated giant cells. She was successfully treated with oral prednisone. Scar sarcoidosis recurred twice in a 7-year follow-up period without accompanying systemic sarcoidosis. Vitiligo appeared with the last relapse of scar sarcoidosis. The case we present is of interest due to the recurrent attacks of scar sarcoidosis in a patient during the remission period of systemic sarcoidosis. Another aspect of this case is the association of the disease with vitiligo without any sign of an autoimmune disease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cicatrix / etiology
  • Cicatrix / pathology*
  • Female
  • Humans
  • Recurrence
  • Sarcoidosis / etiology*
  • Sarcoidosis / pathology*
  • Sarcoidosis / therapy
  • Thyroidectomy / adverse effects
  • Vitiligo / complications*