Hybrid total knee arthroplasty in which the femoral component is cementless and the tibial component is cemented remains controversial. We report on the long-term results of 65 total knee arthroplasties followed for an average of 15 years. There were 18 revisions (27%); of these, 11 were femoral component revisions. The overall implant survival with revision as the end point was estimated as 64% at 15 years. The femoral component survivorship at 15 years was 72%. Because of the high failure rate, hybrid fixation on the femoral side with this design has been abandoned at our institution; but hybrid fixation with a trabecular metal tibia is currently under investigation.