Organising pneumonia and lung cancer - case report and review of the literature

Pneumonol Alergol Pol. 2007;75(4):394-7.

Abstract

Organising pneumonia (OP) is a distinct clinicopathological entity resulting from pulmonary reaction to noxious environmental or endogenous factors, but also idiopathic cases have been noted. Frequently, small foci of OP accompany lung cancer infiltrations. Also OP is sometimes a reaction to radio- or chemotherapy, but it is rarely a predominant lesion in the course of lung cancer. We present the case of 65-year-old patient who presented with fever, dry cough, exertional dyspnoea and pneumonic consolidation in the right lower lobe. Bronchoscopy revealed squamous carcinoma obstructing the right lower bronchi. He was surgically treated, and the right lower lobe was resected. Pathological examination of a specimen revealed only small infiltration of carcinoma cells in the wall of the bronchi and large confluent areas of organising pneumonia. Surgery was a sufficient treatment for both diseases. Six months later he was in good condition without any pulmonary infiltrations. To sum up, a case of endobronchial squamous cell carcinoma in stage T1N0M0 with predominant clinical and radiological signs of OP is presented.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Carcinoma, Squamous Cell / complications
  • Carcinoma, Squamous Cell / pathology*
  • Carcinoma, Squamous Cell / surgery*
  • Cough / etiology
  • Cryptogenic Organizing Pneumonia / complications
  • Cryptogenic Organizing Pneumonia / pathology*
  • Cryptogenic Organizing Pneumonia / surgery*
  • Dyspnea / etiology
  • Fever / etiology
  • Humans
  • Lung Neoplasms / complications
  • Lung Neoplasms / pathology*
  • Lung Neoplasms / surgery*
  • Male
  • Treatment Outcome